CHLOROQUINE AND MEFLOQUINE RESISTANCE PROFILES ARE NOT RELATED TO THE CIRCUMSPOROZOITE PROTEIN (CSP) VK210 SUBTYPES IN FIELD ISOLATES OF PLASMODIUM VIVAX FROM MANAUS, BRAZILIAN AMAZON

BACKGROUND The central repetitive region (CRR) of the Plasmodium vivax circumsporozoite surface protein (CSP) is composed of a repetitive redken shades 9gi sequence that is characterised by three variants: VK210, VK247 and P.vivax-like.The most important challenge in the treatment of P.vivax infection is the possibility of differential response bas

The measurement and treatment of acute pain in animals is essential from a welfare perspective.Valid pain-related outcome measures are also crucial for ensuring reliable and translatable findings in veterinary clinical trials.The short form of the Glasgow Composite Measure Pain Scale (CMPS-SF) is a multi-item behavioral pain sawgrass virtuoso sg500

Abstract Background Multidrug-resistant tuberculosis (MDR/RR-TB) is a major global health challenge, disproportionately affecting low- and lower-middle-income countries (LLMICs).The World Health Organization (WHO) generates guidance to address the problem.Here, we explore the extent to which guidance and related knowledge are generated by experts l

Recovery of still-soft tissue structures, including blood vessels and osteocytes, from dinosaur bone orange zinger tomato after demineralization was reported in 2005 and in subsequent publications.Despite multiple lines of evidence supporting an endogenous source, it was proposed that these structures arose from contamination from biofilm-forming o

Introduction: A hospital is an institution for health care acure face lotion providing treatment by specialized staff and equipment, more often but not always providing for longer-term patient stays.Today, hospitals are very complex institution, not only survive in dynamic environment but also make a profit based on their services.The aimed of this